A bubbling hot casserole dish filled with tender catfish, plump shrimp, and cavatappi pasta in a creamy white alfredo sauce. Indulge in a seafood feast with our irresistible Catfish Shrimp Alfredo Casserole!

Creamy Catfish & Shrimp Alfredo Casserole: Double the Seafood, Double the Flavor!


Looking for a dish that combines the flavors of the sea with creamy, indulgent Alfredo sauce? Look no further than our Catfish Shrimp Alfredo Casserole recipe. This mouthwatering dish is perfect for a cozy family dinner or a special occasion. Packed with bold flavors and easy to prepare, it’s sure to become a favorite in your household.


To make our Catfish Shrimp Alfredo Casserole, you’ll need the following ingredients:

  • 1/2 lb catfish, boned and cut into pieces
  • 3 green onions, chopped
  • 1 tbsp garlic-flavored olive oil
  • 16 oz penne pasta, cooked
  • 1 tsp parsley
  • 1/2 lb shrimp, peeled
  • 1 (6 oz) can mushrooms
  • 16 oz Alfredo sauce (we recommend Ragu Garlic Flavored)
  • 1/2 cup Parmesan cheese


  1. Cook Catfish and Green Onions: In a skillet, heat the garlic-flavored olive oil over medium heat. Add the catfish pieces and chopped green onions, and cook for about 5 minutes, or until the catfish is cooked through and the onions are soft.
  2. Combine Ingredients: In a large mixing bowl, combine the cooked penne pasta with the cooked catfish and green onions. Add the parsley and uncooked shrimp to the bowl.
  3. Add Mushrooms and Alfredo Sauce: Drain the can of mushrooms, reserving the liquid. Add the mushrooms, along with the reserved liquid, to the mixing bowl. Pour the Alfredo sauce over the mixture and toss until everything is evenly coated.
  4. Prepare Casserole: Preheat your oven to 425 degrees Fahrenheit. Spray a 9x11x2 inch baking dish with cooking spray. Transfer the pasta mixture to the prepared baking dish, making sure the noodles are evenly distributed.
  5. Top with Parmesan Cheese: Sprinkle the grated Parmesan cheese over the top of the casserole, ensuring that it covers the entire surface.
  6. Bake: Place the baking dish in the preheated oven and bake for 25 minutes, or until the casserole is bubbly and the cheese is golden brown.
  7. Serve and Enjoy: Once the casserole is done baking, remove it from the oven and let it cool for a few minutes before serving. Serve hot and enjoy the delicious flavors of this Catfish Shrimp Alfredo Casserole.


Our Catfish Shrimp Alfredo Casserole is a delightful combination of flavors and textures that is sure to please even the pickiest eaters. Whether you’re cooking for your family or entertaining guests, this dish is sure to impress. Give it a try for your next dinner party or weeknight meal and prepare to be amazed!

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